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Cox J, Neuhauser N, Michalski A, Scheltema RA, Olsen JV, Mann M

Comprising a sequence of 15 precisely sequenced amino acids, it is an isolated analogue of a naturally occurring protective polypeptide discovered in human gastric juice

Given the promising beneficial effects of MOTS-c in regulating metabolic homeostasis, the therapeutic implications in obesity and diabetes are evident [23]

In HPG axis terms, peptideinduced increases in IGF1 may blunt central inhibitory signals and re-establish more youthful gonadotropin rhythms

Early diagnosis and treatment can help prevent long-term complications and improve outcomes

Buckley 2007)