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Science 304 : 843846

Researchers have found in animal models that just by consuming choline itself, concentrations of carnitine increase in skeletal muscle, as does a loss in total body fat [4]

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While the molecular mechanisms of APAP hepatotoxicity are diverse and include different players, including innate immune response, in this review we will focus on the mitochondriallysosomal axis, which has emerged as a novel liason in several pathologies, including lysosomal storage diseases (Torres et al., 2017a), to pinpoint its role in APAP-mediated hepatotoxicity

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10.1016/j.bbagen.2019.129487 43