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Here, we describe the preclinical pharmacokinetics (PK) of EDP-514, a potent and selective class II core assembly modulator, with Fast Track designation from the FDA

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A healthy body is designed to "recycle" glutathione back into its active state, but high levels of environmental stress can overwhelm this recycling process

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Body weight plays a role in this variation, though it is not the only factor

Besides the initial short-lasting increase of the intraocular pressure upon retrobulbar application, intraocular pressure was continuously normal, and the data were not specifically shown