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Modulate Inflammation: While some inflammation is necessary for healing, chronic inflammation is destructive

From the third day of immunization, melatonin (Sigma-Aldrich) was administered intraperitoneally (10 mg/kg or 80 mg/kg in solution that contains 4% DMSO and 96% PBS)

Some species of experimental animals retain NCs throughout life, whereas others lose them during development and ageing, which may considerably influence experimental outcomes

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Notably, p53 plays a significant role in the regulation of glutathione (GSH) production

Antioxidants like vitamin C are being studied for their ability to reduce oxidative stress, which is often elevated in children with ASD