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Sakamoto, S., Kabe, Y., Hatakeyama, M., Yamaguchi, Y

doi: 10.1016/S0140-6736(20)30628-0 7 IwasakiMSaitoJZhaoHSakamotoAHirotaKMaD

Glutathione peroxidase inhibits cell death and glial activation following experimental stroke

Its anti-inflammatory mechanisms are enacted through the downregulation of pro-inflammatory cytokines such as IL-1, IL-6, and TNF-, along with the inhibition of NF-B signaling, thus alleviating neuroinflammation that is implicated in the etiology of depressive disorders (54)