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Prostaglandins, Leukotrienes and Essential Fatty Acids 2004;70:309-319

Concurrently, SCFAs enhance intestinal barrier integrity by upregulating tight junction proteins (e.g., occludin), which reduces systemic lipopolysaccharide (LPS) leakage and inhibits TLR4/NF-B-driven synovial inflammation (24, 25)

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Oligomeric structure of Hpy GS Although a hexamer of Hpy GS apo was present in each asymmetric unit of the crystal, it could be used to generate a dodecamer with 62 symmetry by stacking two hexameric rings face-to-face (Fig