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doi: 10.1186/s12929-019-0565-2

FAM134B inhibits Ca 2+ hypo-transduction in the mitochondria-associated ER membrane (MAM) by the inositol-1,4,5-trisphosphate receptor (IP3R)-glucose regulatory protein 75 (Grp75)-voltage-dependent anion channel (VDAC) complex, which is involved in MAM formation