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Clinical candidate VT-1161s antiparasitic effectin vitro, activity in a murine model of Chagas disease, and structural characterization in complex with the target enzyme CYP51 fromTrypanosoma cruzi

J.Long-acting mucoadhesive thermogels for improving topical treatments of dry eye disease

Boone KM, Klebanoff MA, Rogers LK, Rausch J, Coury DL, Keim SA

Glutathione Glutathione is a powerful antioxidant in the body

We and others have shown that short-term glucose stimulation, which increases prooxidant status via cytoplasmic NOX4, is necessary for efficient insulin secretion, whereas long-term stimulation, which tends to induce oxidative stress, can lead to the development of T2D ( The most important, but still technically elusive problem in redox signaling is the compartmentalization of redox status

Yang S, Lu S, Ren L, Bian S, Zhao D, Liu M, Wang J