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Activation of aerobic glycolysis-related bypass pathways Increased glycolysis simultaneously activates multiple self-associated bypass pathways, among which the PPP provides the raw material for purine and pyrimidine nucleotide synthesis and maintains redox homeostasis for cancer cell growth, which largely depends on the activity of glucose-6-phosphate dehydrogenase (G6PD), as it catalyzes the first step of the glucose-6-phosphate shift to the PPP [46]

ethers, acetals, ketones, quinones, aldehydes, peroxides A61K47/14Esters of carboxylic acids, e.g

Preliminary clinical observations and isolated case reports have described potential therapeutic benefits associated with BPC-157 and TB-500

** Patient 6 moved out of the area and did not complete the study

doi: 10.1016/j.iotech.2022.100070 66 StortiPVescoviniRCostaFMarchicaVToscaniDDalla PalmaBet al