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It came much easier on the 2nd dose for sure

While some insurance plans may cover B12 injections for diagnosed deficiencies, coverage for weight management purposes may often require specific medical documentation and prior authorization

Certain health conditions such as intestinal or stomach problems, poor nutrition, cancer, HIV, pregnancy, old age, veganism and alcoholism can cause vitamin B12 deficiency

This may also be due to the autoimmune attack on the parietal cells of the stomach in pernicious anemia

When insulin levels are high (like right after a meal), it chemically blocks the lipolytic (fat-burning) pathways

Pyridoxine-inactivating Drugs: Certain medications and drugs reduce or inactivate Pyridoxine, a form of vitamin B6