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It develops when a combination of factors converge inside a hair follicle: excess sebum production by the sebaceous gland, a buildup of dead skin cells that block the pore, colonization by Cutibacterium acnes (the bacteria involved in inflammatory acne), and an inflammatory response from the immune system

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It also enables you to use sugar more efficiently. Thats important because when blood sugar levels get out of whack, theyve been shown to alter certain hormones, metabolic processes and fat cells in a way that promotes weight gain