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it could be reduced within the ER by a glutathione reductase, it could be transported to the cytosol for reduction, or it could be secreted from the cell

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Luc, JG, Fowler, CS, Eisenberg, SB, Estrera, AL, Wolf, RK, Choi, CW, Lawton, JS, Martin, LW, Nesbitt, JC, Reznik, S, Nguyen, TC, Vaporciyan, AA, Antonoff, MB

Molecular mechanisms of chondrocyte proliferation and differentiation