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While we were unable to ask respondents to explain the reasons behind their treatment preferences, the concordance between the degree of variation within a symptom (as measured by average NGV) and the quantity and quality of available clinical evidence suggests this as an important factor in practice variation

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Neuropediatrics 27:115123 Kolker S, Christensen E, Leonard JV, Greenberg CR, Boneh A, Burlina AB, Burlina AP, Dixon M, Duran M, Garcia Cazorla A, Goodman SI, Koeller DM, Kyllerman M, Muhlhausen C, Muller E, Okun JG, Wilcken B, Hoffmann GF, Burgard P (2011) Diagnosis and management of glutaric aciduria type Irevised recommendations

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Ethyl (R)-4-chloro-3-hydroxybutyrate was detected at 11.7 min, whereas ethyl (S)-4-chloro-3-hydroxybutyrate was detected at 12.1 min