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[DOI] [PubMed] [Google Scholar] 86.Checkley W., West K.P., Wise R.A., Wu L., LeClerq S.C., Khatry S., Katz J., Christian P., Tielsch J.M., Sommer A

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Gao 2023 (human GLP1R-variant series) puts a number on it at the GLP-1 receptor: cAMP output saturates at roughly 10% (103%) receptor surface expression, so full effect sits far below full occupancy