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Doxorubicin (DOX), an antineoplastic drug widely used in anticancer treatment, can increase cardiotoxicity, lead to myocardial injury and heart failure (Wallace et al., 2020)

Selenium also appears to have a role in the resistance of animals to disease being involved in the production of antibodies and in eliminating pathogens

Asian Journal of Sports Medicine: Vol.8, issue 1

Heltberg, M

BondaDJWangXPerryGNunomuraATabatonMZhuXet al

Additionally, it is believed that glutamate-mediated oxidative stress due to increased ROS production has been shown to be a biphasic event in a way that glutamate induces a primary surge in ROS production after 6-8 h and followed by a secondary boost after 18 h [43]