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These mitochondrial interactions offer glimpses of the viral effect on glycolytic and oxidative phosphorylation pathways and the potential side effects

In f , s , the box plots show the median (centre) and the 25th and 75th percentiles (bounds of box), and the whiskers indicate the minimum and maximum values

Importantly, GPX4 was positively correlated with resistance of lung cancer cells to L-685458, lapatinib, paposilli, and topotecan, suggesting that targeting System X c /GSH/GPX4 axis could overcome drug resistance (Zhang et al., 2020