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If there is no IF or limited secretion, it is not reabsorbed in the enterohepatic circuit and is excreted, meaning that the deficiency will occur sooner (as the enterohepatic recycling circuit is failing), just as if the dietary intake is inadequate, there will come a point where enterohepatic circulation will not be sufficient

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It can change the way cells react to treatment

Proper storage ensures consistent results across weekly dosing studies

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