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Clinical translation of this co-delivery system faces challenges in scalability and biocompatibility validation

Retrieved 8 August 2016

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Perraud et al., 2005), and nuclei through the sequential actions of nuclear enzyme poly-ADPR polymerase (PARP) and poly-ADPR glycohydrolase (PARG) in response to DNA damage and PARP stimulation (Esposito and Cuzzocrea, 2009

Gut microbiota-derived components (e.g., LPS, peptidoglycan) and metabolites (e.g., SCFAs, TMAO) interact with hepatocytes via the portal vein, influencing glucose and lipid metabolism, immune responses, and redox balance, thereby driving MAFLD progression 118