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Eukaryot Cell 5 , 272276, doi: 10.1128/EC.5.2.272-276.2006 (2006)

mTOR activation involves multiple interconnected signaling pathways

This study broadens our understanding about the intersection of amino acid metabolism and ferroptosis regulation, providing insight into the underlying mechanisms and suggesting the methionine-SAM axis is a promising therapeutic strategy to treat ferroptosis-related diseases