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Human survivin and Trypanosoma Cruzi calreticulin act in synergy against a murine melanoma in vivo

Virz GM, Morisi N, Marturano D, Milan Manani S, Tantillo I, Ronco C, et al

Excessively high iron ion levels within cells can lead to hydroxyl radical production via the Fenton reaction through interactions with hydrogen peroxide, thus promoting ROS production, lipid peroxidation, and the generation of oxidative byproducts such as MDA that are highly toxic, contributing to ferroptosis (Zeng et al., 2019)

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