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To investigate the effect of RRM2 on the cell cycle of THCA, we examined the effects of RRM2 knockdown ( RRM2 -KD) and overexpression ( RRM2 -OE) on cell cycle distribution in the TPC-1 and IHH4 cell lines, respectively, using flow cytometry

Development of papules or pustules in areas that were previously clear

By reducing tyrosinase activity, it shifts production from eumelanin (darker pigment) to pheomelanin (lighter pigment), resulting in a gradual lightening effect

Identification of remarkable metabolites by partial least squares-discriminatory analysis and orthogonal partial least squares-discriminatory analysis Seventy-two metabolites, including 29 organic acids, 16 free fatty acids, and 27 amino acids, whose intra- and inter-coefficients of variation were less than 30%, were quantified

Complex I catalyzes the oxidation of reduced NADH and the reduction of ubiquinone with the contribution of two electrons and four protons, promoting the formation of a proton gradient across the IMM [35]

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