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Overall, the compliance rate was high, with more than 80% of tablets taken in each trial group

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M2-like TAMs promote tumor angiogenesis by producing pro-angiogenic growth factors (VEGF, EGF, FGF family, and PDGF-b), angiogenic CXC chemokines (CXCL8/IL-8 and CXCL12, also known as SDF-1), and angiogenesis-associated factors (TGF-b, TNF-, and thymidine phosphorylase) 51,52

[DOI] [PubMed] [Google Scholar] Becejac T, Cesarec V, Drmic D, et al

Dihydronicotinamide riboside (NRH), a reduced form of NR with oral bioavailability, is developed to overcome these limitations