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Maternal obesity induces the meiotic defects and epigenetic alterations during fetal oocyte development

This impairment is specifically in the development of anthers and pollens, thus resulting in male sterility and producing parthenocarpic (seedless) fruits or having unviable seeds (Deslous et al., 2021)

Pitzer et al., 2019)

We therefore introduced the Aplnr-CreERT2 line into the Flt4 lox/lox background

IGF-1 has been shown to have anti-apoptotic effects in many cells, including oligodendrocytes (those cells responsible for myelination in the brain)

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