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Description

Mutat Res Genet Toxicol Environ Mutagen 827:5967

Board Certified Primary Care Physician Dr

PMID: 9403785

[DOI] [PMC free article] [PubMed] [Google Scholar] 23.Matsumoto K, Saga Y, Ikemura T, Sakakura T, Chiquet-Ehrismann R

In the mature DPP1 molecule, the exclusion domain binds the catalytic domain through non-covalent interactions and restricts substrate access to regions upstream of the S2 subsite via steric hindrance, determining DPP1s unique dipeptidyl peptidase activity ( The DPP1 active site structure reflects the molecular basis for its broad substrate specificity