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Description

Simponi Aria offers convenient IV dosing, long-lasting effect, inflammation reduction, and joint damage reduction

Kuroki R, Sadamoto Y, Imamura M, Abe Y, Higuchi K, Kato K, Koga T, Furue M

It's not clinically equivalent to replacement but provides an alternative option for suitable candidates

PubChem Reference: View compound profile on NIH PubChem Key Characteristics MOLECULAR PROFILE Formula: C 38 H 49 N 9 O 5 Weight: 711.86 g/mol CAS: 170851-70-4 Structure: Aib-His-D-2-Nal-D-Phe-Lys PHYSICAL PROPERTIES Form: White to off-white lyophilized powder Solubility: Readily dissolves in water Selectivity: High receptor selectivity Storage: Keep refrigerated 3646 F (28 C)

These cell lines were cultured in RPMI1640 medium (Gibco cat#11875119) supplemented with 5% Fetal Bovine Serum (BioWest, cat#S1620), 1% Penicillin/Streptomycin (Fischer Scientific, cat#15-140-122) and 1ug/ml Puromycin (Gibco, cat#A1113802)