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doi: 10.3389/fphar.2021.685116 Received 24 March 2021 Accepted 13 July 2021 Published 11 November 2021 Volume 12 - 2021 Edited by Gokhan Zengin, Selcuk University, Turkey Reviewed by Vuyisile Samuel Thibane, University of South Africa, South Africa Erna Karalija, University of Sarajevo, Bosnia and Herzegovina Updates Copyright 2021 Pang, Wu, He, Nian, Lei, Yao, Guo and Zeng