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This compound is a cyclic hydroxylamine that is oxidized upon the reaction with superoxide to generate a more stable radical called nitroxide

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Endothelial cells were then released from beads and reselected with magnetic beads conjugated with anti-mouse Podoplanin anti-PDPN (8.1.1) (1: 50, BioLegend) in order to obtain CD102+ and Podoplanin+ cells

Hemodynamic changes induced by PH and pro-inflammatory cytokines are also known to cause alteration of redox potential affecting the stress-activated signaling cascades