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People following cutting or weight-loss programs

Measurements were corrected for background signal using a CD buffer sample

Doses exceeding 20 mg per day are generally not recommended, as the long-term safety of higher doses is not well-established

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Another TCA cycle metabolite, citrate, gets transported into the cytosol and utilized for fatty acid synthesis to support membrane biogenesis and synthesis of pro-inflammatory lipid mediators, namely prostaglandins

The updated report also emphasizes that the PHD is not rigidly prescriptive