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Iodine and brain-targeted hormone regulation Iodine is indispensable for thyroid hormone synthesis and, through this role, exerts profound indirect effects on the brain (140)

A deeper understanding of the ferroptosis mechanism in the development of HNC will facilitate the development of relevant biomarkers, construction of risk prediction models, screening of potential therapeutic targets, improvement of prognostic assessment methods, management of high-risk populations and advancement of precision medicine

46 Progesterone may also be a factor in fibromyalgia pain, with women in a small clinical study reporting greater fibromyalgia pain severity on days when their progesterone levels were lower

NRF2, a member of the NFE2 family of transcription factors, is not essential for murine erythropoiesis, growth, and development

Volpini et al

Nature 414: 782-787