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Similarly, a modified formula of Sishenwan, Fufangxiaopi, alleviated colitis-related symptoms in mice by regulating gut microbiota and significantly enhancing the expression of claudin-3, occludin, and ZO-1, thereby maintaining the intestinal barriers integrity (Liu K

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Ten patients with GBM were included in this study

Further evidence of ongoing inflammation in GD is the elevation of ICAM-1, IL-6 and IL-8 cytokines seen in hyperthyroid patients (217, 226)

Since DCAF16 is already known to support targeted protein degradation 69 and several DCAF16-dependent BRD4 degraders are already known 25,27,38 , we focused our subsequent efforts on SCF FBXO3 , which has not previously been coopted for targeted protein degradation