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People with pernicious anemia, may benefit from sublingual B12 as they lack intrinsic factor and have a lot of trouble absorbing B12 through their digestive system (Ankar, 2020)

Rybelsus (semaglutide) is a GLP-1 receptor agonist that stimulates insulin secretion, suppresses glucagon release, and slows gastric emptying to control blood glucose in type 2 diabetes