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Supporting Mood and Mental Well-being: B-12 plays a role in the production of neurotransmitters that regulate mood

Nature 418 , 650654 (2002)

Finally, it is important to avoid strenuous physical activity immediately after receiving a B12 shot

Vegans and "patients with diseases like Crohn's and colitis as well as people with pernicious anemia are also particularly vulnerable to deficiency," added Silverstein