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It is also more common in people who have poor sanitation and hygiene practices

The mRNA expression of SERCA (Sarco/ER Ca 2+ -ATPase for influx) and IP3R (inositol trisphosphate (IP3) receptor for efflux) was also examined, revealing a decrease in SERCA (the target of thapsigargin (TG)) and an increase in the most prominent isoform, ITPR3 (Supplementary Figure S11e and S11f)

Graphical Abstract 1 Introduction Stress reaction refers to the physiological and psychological responses of the body when exposed to stressors (Selye, 1998)