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When a cell has higher levels of GSSG, then it can be implied that more oxidative stress has occurred within the cell

Xenograft tumors (generated through the implantation of human tumors in mice) increased substantially following the administration of vitamins C and E and N-acetylcysteine in a BACH1-dependent fashion under normoxia

Chronic ethanol consumption results in atypical liver injury in copper/zinc superoxide dismutase deficient mice

The essential role of LA in barrier function was determined in several animal experiments similar to those conducted by Burr and Burr (1, 2)

35 As discussed earlier, trauma, coupled with an associated genotype, can damage keratinocytes, leading to the expression of IFN and TNF, activation of dendritic cells, and production of IL-23

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