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Data was analyzed by a repeated-measures analysis of variance (ANOVA)

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Each platform used 200 L of elution buffer

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Primary research applications: In-vitro and pre-clinical models of skin regeneration, wound repair, hair-follicle biology, and tissue remodeling [3]

Second, VEGF changes the activation of endothelial cells, and induces the expression of a series of endothelial cell genes from different sources under hypoxic conditions (40), including the expression of procoagulant factor, plasminogen activator inhibitor-1 (PAI-1), matrix metalloproteinase (MMP), interstitial collagenase and tissue factor, to degrade the extracellular matrix around blood vessels (41) to promote the release of pro-angiogenic factors stored in the extracellular matrix (42) thus inducing vascularization