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This has been a great opportunity to work with radiation oncologists around the country to write up and publish unique cases for which published data and management guidelines are missing.

The presence of anti-inflammatory cytokines such as IL-10, IL-4, or IL-13 induces the appearance of neuroprotective reactive astrocytes, which in turn have the capacity to release IL-4, IL-10, and TGF- (Oksanen et al., 2019)