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490 Moreover, the deletion of GDI likely affected neuronal vesicle trafficking, thereby altering short-term synaptic plasticity and causing short-term memory deficits

Hjorth-Srensen B, Hoffmann ER, Lissin NM, Sewell AK, Jakobsen BK (2001) Activation of heat shock transcription factor in yeast is not influenced by the levels of expression of heat shock proteins

Glutathione (GSH) is a central component of the antioxidant defense system, and disruption of GSH homeostasis can lead to the accumulation of pyroglutamate (PGA), which is detectable in plasma

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Hence, a carnitine deficit starts a vicious cycle