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MR is strongly recommended as a means of prioritizing drug targets for cardiovascular research, to avoid expensive failures in phase III randomized controlled trials (RCTs) [18, 19] and to identify mechanistic targets of intervention, complementary to RCTs [19]

Vitetta L, Briskey D, Alford H, Hall S, Coulson S

Winder-Patel, B

Because the annular plane did not demonstrate increased excursion with respect to an external reference point, the authors concluded that this was due to traction of the PM towards the MV rather than annular hypermobility towards the apex

A dopamine agonist is a drug containing a molecule that binds to and activates dopamine receptors, similar to dopamine itself, thus compensating for low dopamine levels