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Description

We measured the abundance of 14 metabolites related to the one carbon pathway in HepG2 cells, including methionine, SAM, SAH, and glutathione

Methods: Retrospective analysis using the 2020 National Inpatient Sample dataset, and utilizing relevant ICD-10-CM codes to calculate the adjusted odds ratio (AOR)

Although the direct interaction of CD44 and OTUB1 is much lower in comparison to OTUB1-xCT interaction, nevertheless, this three-protein complex is thought to stabilize xCT more effectively, possibly further enhancing chemoresistance