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10.1016/j.chest.2018.04.008 60

[28] It is a genetic disorder that affects the lungs, but also the pancreas, liver, kidneys, and intestine

Bromodomain and extraterminal (BET) protein inhibition sensitize BRAFV600E colorectal cancer to standard targeted therapies

In human studies, Nrf2 suppression has been linked to cataract formation in lenses collected from diabetic and older patients, with the upregulation of Keap1 (an Nrf2 suppressor) found in these individuals

However, in the context of chronic ethanol consumption, the dysregulation of apoptotic pathways can lead to excessive neuronal loss, which is implicated in the pathophysiology of depression (Hicks et al