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In the OASIS-1 study, 13% of participants (people with obesity without diabetes) receiving oral semaglutide 50 mg experienced altered skin sensation events compared to 1% with placebo - these events were generally mild to moderate in severity, occurred during dose escalation to the higher doses and resolved without requiring permanent treatment discontinuation [21]

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(2) J M Monti, J Debellis, P Alterwain, T Pellejero, et al (1987) Study of delta sleep-inducing peptide efficacy in improving sleep on short-term administration to chronic insomniacs International Journal of Clinical Pharmacological Research, 1987, Volume 7 (Issue 2), Pages 105-10

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