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Poppe 1 , Alexander Khaw 2 , Darren Ferguson 3 , David Volders 3 , Grant Stotts 4 , Ariesteidis Katsanos 5 , Gregory Jacquin 1 1 Centre Hospitalier de lUniversit de Montreal, Montreal, Canada, 2 London Health Sciences Centre, Western University, London, Canada, 3 Dalhousie University, Halifax, Canada, 4 Ottawa Hospital Research Institute, Ottawa, Canada, 5 McMaster University, Hamilton, Canada Background and Aims: There are several possible sedation strategies during endovascular therapy for acute ischemic stroke, including general anesthesia, conscious sedation, and local anesthesia

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In another embodiment, monocytes and/or macrophages having a reduced inflammatory phenotype exhibit one or more of the following properties upon contact with one or more agents: a) (ii) reduced expression and/or secretion of cluster of differentiation 80(CD80), CD86, MHCII, MHCI, interleukin 1-beta (IL-1 beta), IL-6, CCL3, CCL4, CXCL10, CXCL9, GM-CSF and/or tumor necrosis factor alpha (TNF-alpha)

Palmer et al., 2008