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Further research has shown that cyclin-dependent kinase-phosphorylated DAB2IP enhances polo-like kinase 1 pathway activity, and inhibits the ubiquitination and degradation of cell division cycle 20 by interacting with it, thereby stabilizing the anaphase promoting complex

In contrast, rats injected with iohexol exhibited diminished CT signals, lacking contrast enhancement at elevated radiation energies (Figure S10B)

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This is direct clinical evidence of a peptide modulating tight junction function in humans