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Description

Mechanistic/structural-based NAD analogs CD38 inhibitors This class of CD38 inhibitors was developed via modification of the nicotinamide ribose in the molecule of NAD and NMN [58-59, 66-67]

Doyle et al., 2012

Concomitantly, sera containing high levels of IgG4 provided few antibody-mediated effector functions, such as antibody-dependent phagocytosis or complement deposition, despite increased antibody affinity and neutralizing capacity in our study