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SF (28.2 mol/kg an hour after SCI induction) activation of Nrf2 post-SCI improved locomotor function and reduced inflammatory damage, neuron death, and spinal cord edema, while neurological deficits were more severe and the protective effect of SF was not observed in Nrf2 deficient mice (105)

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Reduced mitochondrial DNA copy number is a biomarker of Parkinsons disease

In the mitochondria, superoxide is produced as a byproduct of oxidative phosphorylation (207)

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