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Acknowledgements The authors gratefully acknowledge the institutional support provided by their respective affiliations for facilitating access to scientific resources and databases necessary for completing this review

In particular, the relevance of the ATB 0,+ -mediated carnitine transport, in patients with PCD, may be explained considering that this protein is highly expressed in the intestine (Figure 2)

1 We chose to use CTCAE data as the primary CIPN endpoint because they were available in all trial participants, whereas PRO data 62 were available only in the subset of patients that participated in the DELCaP substudy 17 and because of our concerns regarding the use of PRO data in CIPN biomarker analyses