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This is composed of four major protein complexes (I-IV) that generate a charge and proton gradient across the inner mitochondrial membrane (IMM) which drives the ATP synthesis in complex V, known as ATP synthase

It was found to be useful in experimental models of various peripheral and central nervous system diseases such as diabetic neuropathy, multiple sclerosis, cerebral ischemia-reperfusion, excitotoxic amino brain cerebral ischemia, autoimmune encephalomyelitis [17]

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[DOI] [PMC free article] [PubMed] [Google Scholar] 219.Li Y, et al

There was no significant retardation of probe reduction in either gshA or gshA oppC cells, at least when compared to the addition of Gor without NADPH (Figure 6E, F)