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Dehp reduces thyroid hormones Via interacting with hormone synthesis-related proteins, deiodinases, transthyretin, receptors, and hepatic enzymes in rats

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In aged dermis, fibroblasts are reduced in both number and capacity to synthesise ECM proteins [17] contributing to age-associated atrophy

Research has also investigated the connection between MTHFR polymorphisms and (amnestic) Mild Cognitive Impairment (aMCI), which is considered a transitional stage between aging and the pathological state of dementia [86,88]