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[17]Ismael MA, Elyamine AM, et al

Despite the initiation of clinical trials across various programs and the endorsement of numerous phase 2 and 3 trials, 261,262,263,264,265 the presence of side effects or toxicity remains indeterminate, necessitating prolonged drug usage and further pertinent data

These induced DNA lesions subsequently engage the cells intrinsic repair pathways, predominantly activating either the error-prone non-homologous end joining (NHEJ) pathway for gene knockout or the high-fidelity homology-directed repair (HDR) pathway for precise gene correction, thereby enabling diverse genomic modifications (78)

The zinc Micro-encapsulated in this health food supplement also contributes to the normal functioning of the immune system while being beneficial for the skin

Funding The authors would like to acknowledge the BIG-BIRAC Grant awarded to Dr

10.13422/j.cnki.syfjx.2017040145 127 RandrianarisoaE.Lehn-StefanA.WangX.HoeneM.PeterA.HeinzmannS