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166 , 199207.e115 (2013)

Future perspectives In the past few decades, research on the metabolite sensing mechanism has received great attention

Nevertheless, these findings of previously unknown reactions though IsoNet fill the previously unexplored metabolic network, and complement our understanding of the metabolic maps in cellular metabolism

Our data reveal that sustained hypoglycaemia at or below 85 mg dl 1 with concurrent suppression of circulating insulin is sufficient to flip stable adipocytes into a permissive catabolic state (Fig